linkedinIcon  twitterIcon  facebookIcon2

Programs

MS1819 lipase, Phase IIa

  • Non-systemic, yeast derived recombinant enzyme
  • Oral non-systemic capsule for treatment of exocrine pancreatic insufficiency (EPI) in patients with chronic pancreatitis (CP) and cystic fibrosis (CF)
  • Demonstrates superior in vitro characteristics (i.e. high potency, activity in long chain fats, stability in protease and bile salt environments), eliminates pork viral contamination risk
  • Phase IIa in vivo safety and efficacy profile shows promise to improve on standard porcine-derived therapy

AZX1101 beta lactamases, preclinical

  • Oral, non-systemic medicine to act locally in the GI tract to prevent nosocomial (hospital-acquired) infections by resistant bacterial strains induced by parenteral administration of β-lactam antibiotics.